Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.400 None 0.946 297 12 1993 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.400 None 0.961 205 3 1995 2019
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.700 definitive 0.944 36 2 2006 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.400 definitive 0.939 33 0 2000 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.969 32 6 1992 2019
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.400 definitive 1.000 22 2 1998 2019
Entrez Id: 580
Gene Symbol: BARD1
BARD1 		Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.350 definitive 0.938 16 4 2001 2019
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		O43502 RAD51 paralog C 162 0.533 0.692 6.2E-14 0.320 disputed 1.000 9 1 2010 2019
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D 		O75771 RAD51 paralog D 36 0.674 0.385 1.1E-09 0.510 limited 1.000 9 1 2000 2019
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1 		Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 194 0.507 0.731 6.2E-17 0.080 None 0.875 8 0 2007 2019
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		O43543 X-ray repair cross complementing 2 187 0.512 0.731 4.0E-07 0.530 limited 1.000 7 1 1999 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.060 None 0.833 6 0 2002 2019
Entrez Id: 5965
Gene Symbol: RECQL
RECQL 		P46063 RecQ like helicase Enzyme 58 0.615 0.615 1.5E-20 0.320 moderate 1.000 6 0 2005 2019
Entrez Id: 57697
Gene Symbol: FANCM
FANCM 		Q8IYD8 FA complementation group M Enzyme 147 0.543 0.731 2.4E-15 0.050 None 1.000 5 1 2009 2019
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1 		Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 321 0.459 0.808 8.9E-10 0.020 None 1.000 2 0 2015 2019
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		Q9NVI1 FA complementation group I 147 0.543 0.731 8.9E-37 0.020 None 1.000 2 0 2009 2019
Entrez Id: 27022
Gene Symbol: FOXD3
FOXD3 		Q9UJU5 forkhead box D3 Transcription factor 78 0.587 0.692 0.58 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A 		Q03164 lysine methyltransferase 2A 535 0.410 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 22983
Gene Symbol: MAST1
MAST1 		Q9Y2H9 microtubule associated serine/threonine kinase 1 Kinase 41 0.711 0.385 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5429
Gene Symbol: POLH
POLH 		Q9Y253 DNA polymerase eta 44 0.663 0.462 3.5E-09 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2175
Gene Symbol: FANCA
FANCA 		O15360 FA complementation group A 211 0.505 0.731 1.6E-68 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 85348
Gene Symbol: KRT88P
KRT88P 		keratin 88 pseudogene 24 0.705 0.385 0.010 None 1.000 1 0 2019 2019
Entrez Id: 9156
Gene Symbol: EXO1
EXO1 		Q9UQ84 exonuclease 1 Enzyme 87 0.578 0.692 8.1E-13 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 8493
Gene Symbol: PPM1D
PPM1D 		O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 177 0.513 0.808 2.2E-11 0.310 None 1.000 1 0 2019 2019
Entrez Id: 9400
Gene Symbol: RECQL5
RECQL5 		O94762 RecQ like helicase 5 Enzyme 28 0.682 0.500 3.2E-18 0.010 None 1.000 1 0 2019 2019